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project administration and funding acquisition: N.I.M.F

Mechanism Investigation: Oral BPC-157 research raises important mechanistic questions: Local vs

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Mechanistically, glutamine withdrawal can induce rapid apoptosis in Myc-transformed cells, whereas ammonia released from glutamine-catabolizing tumor cells may act in an autocrine or paracrine manner to stimulate autophagy and promote survival under nutrient-limited or hostile microenvironmental conditions (Wise et al., 2008